Jardiance is a daily oral medication that is utilized to regulate blood sugar levels in those who suffer from type 2 diabetes.
This is achieved by aiding the kidneys in removing glucose from bloodstreams through the urine.
Jardiance isn’t designed for weight loss or blood pressure control However, it can assist in both. It can be used as part of a plan of treatment that could include exercise diet, and medical treatment.
This drug received approval from the European Commission in May 2014. Since it is a relatively new medication that is still in its initial stages, the long-term effects of several years are not established.
The trade name is Jardiance
Genric Name: Empagliflozin
Class of drug: SGLT2 inhibitors
Manufacturer Boehringer Ingelheim and Lilly Diabetes
What does Jardiance aid with type 2 diabetes?
By eliminating excess levels of glucose in the body via the urine, Jardiance assists in enhance glycemic control for those suffering from the type 2 form of diabetes. This could lead to improved HbA1c level, which could lower the risk of developing complications related to diabetes.
Since glucose is a source of calories and being eliminated by the body. This means that weight reduction may be a result of Jardiance. Because type 2 diabetes is highly related to weight – approximately 90% of people who are newly diagnosed with type 2 diabetes have a weight that is above the ideal which is beneficial to keeping an ideal weight.
Jardiance is utilized as a component of a treatment program, and it is crucial to keep other aspects in check including physical fitness in addition to Jardiance treatment.
Mechanism of action
Empagliflozin can be described as an SGLT2 inhibitor, a class of medications that aids in stopping the sodium-glucose transportation proteins that are filtered out of kidneys’ bloodstream and reabsorbed into blood.
Empagliflozin permits a substantial quantity of glucose to be eliminated by urine. It is believed that the SGLT2 proteins account for 90% of the glucose returned to the blood.
Who do you think Jardiance appropriate for?
Jardiance is suggested from the National Institute of Clinical Excellence (NICE) as an option for treating type 2 diabetes with those conditions
When exercise and diet are not sufficient for glucose-control
If metformin isn’t appropriate because of patient intolerance
Jardiance can also be used in conjunction with metformin in cases where patients are at high risk of developing hypoglycemia, or cannot use an or a sulfonylurea. It is also possible to take alongside metformin or a Sulfonylurea.
For help with the Jardiance patient assistance program click here.
Who is not a good candidate for Jardiance?
It is not recommended to use Jardiance If you suffer from:
Type 1 diabetes
Severe kidney problems
Before you take Jardiance the first time, discuss with your doctor if:
Are you suffering from kidney problems?
Are you expecting or planning to be expecting or planning to become
Are you breastfeeding or are you planning to breastfeed?
Are you suffering from liver issues?
Have a low blood pressure
Use blood pressure medications
Are you suffering from high cholesterol levels?
Are you a victim or a history of infections in the urinary tract
Are you 65 or more
Are you following a low-salt diet
What should Jardiance be handled?
Jardiance is taken orally and generally taken every morning. It may be taken either with or without food.
The medication is initially prescribed as a 10mg dosage but the maximum dose is 25 mg. Your doctor can alter the dose of your medication to ensure you are getting the most benefit However, you shouldn’t use Jardiance in lower or higher doses than what is recommended.
If you have missed an dose, it is recommended to start taking it whenever you remember. However, you shouldn’t take an additional dose to make up for the missed medication. If you are nearing the time to take your next dose, it is best to not take the dose you missed previously.
Jardiance must be kept at room temperature, away from heat and moisture, and stored in the original container. It must be ensured that it’s away from the view and reach of young children.
What are the possible side consequences of Jardiance?
The negative side negative effects of Jardiance are:
Urinary problems – whether it’s an urge to urinate frequently or very little or no urine
The increased risk of urinary tract infections
The signs of a genital infection like itching, pain or the appearance of a itchy rash
If taken in conjunction by a medication that lowers blood glucose levels
The increase in cholesterol
Feeling lightheaded or tired
It is important to note that the list above isn’t complete. Please look up the leaflet for patients that comes with the medication for a complete list of adverse negative effects.
What do you do if you have taken an overdose
If you have taken an overdose of Jardiance make contact with your health professional immediately for assistance.
There are many questions about whether SGLT2 inhibitors cause negative long-term impact on the kidneys. Invokana is part of the same drug class as Jardiance and has been associated with a decline in eGFR which is a measure used to assess kidney function.
Based on the European Medicines Agency, the most commonly reported adverse reaction with Jardiance was hypoglycemia. This was seen when it was used in conjunction in conjunction with insulin or sulphonylurea.